Smartox’ ProTx-II, a highly potent Nav1.7 blocker
Interesting work on ProTx-II from the University College of London. ProTx-II is a potent blocker of the voltage-gated sodium channel Nav1.7. Results show that the synthetic Smartox’ ProTx-II is highly active.
View results here: http://discovery.ucl.ac.uk/1467249/1/Zoe%20Wright%20PhD%20Thesis.pdf
ProTx-II is also available with a fluorescent and a biotin tag.
- Cy5-ProTx-II: fluorescent version
- Biotin-ProTx-II: biotinylated version